Effects of Sympathomimetics on Perfused Rat Mesentery

Synopsis

Preparation: perfused rat mesentery. The method of constant volume perfusion of a vascular preparation is demonstrated as well as the measurement of changes in vascular resistance using pressure transducers. The Biovideograph record gives the results of administration of the three sympathomimetics, noradrenaline, adrenaline and isoprenaline and shows that adrenaline possesses the highest potency. Addition of phentolamine markedly inhibits the effects of noradrenaline and adrenaline, whereas propranolol has no antagonist action against noradrenaline. Summarises the experimental evidence for ascribing preponderant sympathomimetic action to an }-adrenoceptor site.

Language

English

Country

Great Britain

Medium

Video; Videocassette. Standard formats. (for use with Biovideograph). col. 30 min.

Year of production

198

Availability

OUT OF DISTRIBUTION

Subjects

Medical sciences

Keywords

drugs; laboratory animals; pharmacology; rats; sympathomimetic drugs

Production Company

Name

University of Bradford

Distributor

Name

Harvard Apparatus

Phone

01732 864001

Address

Fircroft Way
Edenbridge
Kent
TN8 6HE

Notes

No longer distributes videos (5/96)