Sites of Action of Drugs on the Isolated Intestine: Guinea Pig Ileum

Synopsis

Preparation: guinea pig ileum. The presentation includes a brief theoretical introduction to the possible sites of drug action on the longitudinal smooth muscle layer of the intestine, based on a consideration of autonomic nervous system innervation and muscle membrane reactivity. The Biovideograph record shows the initial conditioning stages of the isolated organ preparation, the obtaining of standard submaximal responses to a range of parasympathomimetics with action on nicotine and muscarinic sites followed by the demonstration of selective antagonism using hexamethonium and atropine at the two sites.

Language

English

Country

Great Britain

Medium

Video; Videocassette. Standard formats (for use with Biovideograph). col. 48, 56 min.

Year of production

198

Availability

OUT OF DISTRIBUTION

Subjects

Biology

Keywords

drug action; guinea pigs; ileum; laboratory experiments

Production Company

Name

University of Bradford

Distributor

Name

Harvard Apparatus

Phone

01732 864001

Address

Fircroft Way
Edenbridge
Kent
TN8 6HE

Notes

No longer distributes videos (5/96)