Repairing the Code

Synopsis: Video recording of the Francis Crick Lecture given at the Royal Society on 7 December 2011 by Dr Simon Boulton from Cancer Research UK. DNA, also known as the ‘blue print’ of life, encodes the instructions for the development and function of the vast majority of organisms on our planet. Despite its importance, DNA is intrinsically unstable and is prone to breakage and chemical modifications. If left unrepaired DNA damage can giving rise to mutations, which alter the coding sequence. To counteract the deleterious effects of DNA damage, cells have evolved specialized DNA repair mechanisms. Insights into DNA repair processes and their control have firmly established the importance of DNA repair in ageing and cancer. This talk discusses the damage that can occur to DNA, and the processes which can be used to repair DNA following damage. Dr Boulton discusses the links between DNA repair and ageing and cancer. (60 minutes)
Language: English
Country: Great Britain
Year of release: 2012
Year of production: 2011
Subjects: Biology; Medical sciences
Keywords: ageing; cancer; cell damage; DNA; genetic code

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British Universities Film & Video Council