Cystic Fibrosis

Synopsis

Cystic Fibrosis is an autosomal recessive condition which results in severe respiratory, digestive and other health problems. Although management has improved considerably in the past 20 years it is still a seriously disabling disease.

The video, divided into four sections, discusses the symptoms, diagnostic testing, treatment and biochemical basis of Cystic Fibrosis.

Section one, Presentation, demonstrates the incidence, presenting features and on-going health problems associated with this condition.

Section two, Diagnostic Testing, looks at DNA analysis in the laboratory with the Elucigene CF12 test kit. Following amplication by PCR, DNA samples are separated by electrophoresis to check for possible CF mutations.

Section three, Treatment, is an examination of the combined use of drugs and physiotherapy to reduce the damage caused by the disease.

Section four, Biochemistry, shows how in a normal individual mucus lining the air passages in the lungs is thin because it has a high water content. The role of transmembrane regulators is vital in allowing chloride ions - and water - across cell membranes. The failure of these regulators in cystic fibrosis causes the symptoms of the disease.

Series

Clinical Biochemistry, Series

Language

English

Country

Great Britain

Year of production

2001

Uses

Pre-clincal medical students; students of biochemistry and physiology

Subjects

Medical sciences

Keywords

biochemistry; cystic fibrosis

Distribution Formats

Type

VHS

Price

£35.00

Availability

Sale

Duration/Size

20 min

Year

2002

Production Company

Name

Leeds University Television

Distributor

Name

Educational Broadcasting Services Trust

Address

No longer trading

Notes

Educational and training materials with an emphasis on maths, science and skills development, produced in collaboration with consortia of university and college academics and media departments under the auspices of the Educational Services Broadcasting Trust. Series include Maths for Engineers, Shotlist, and the Skillbank vocational skills training programmes. For sale on DVD or via download. Now ebst online is part of FENC. (www.fenc.org.uk). Now possibly part of Blended Learning Consortium.