Cystic Fibrosis

Synopsis: Cystic Fibrosis is an autosomal recessive condition which results in severe respiratory, digestive and other health problems. Although management has improved considerably in the past 20 years it is still a seriously disabling disease.

The video, divided into four sections, discusses the symptoms, diagnostic testing, treatment and biochemical basis of Cystic Fibrosis.

Section one, Presentation, demonstrates the incidence, presenting features and on-going health problems associated with this condition.

Section two, Diagnostic Testing, looks at DNA analysis in the laboratory with the Elucigene CF12 test kit. Following amplication by PCR, DNA samples are separated by electrophoresis to check for possible CF mutations.

Section three, Treatment, is an examination of the combined use of drugs and physiotherapy to reduce the damage caused by the disease.

Section four, Biochemistry, shows how in a normal individual mucus lining the air passages in the lungs is thin because it has a high water content. The role of transmembrane regulators is vital in allowing chloride ions - and water - across cell membranes. The failure of these regulators in cystic fibrosis causes the symptoms of the disease.
Series: Clinical Biochemistry, Series
Language: English
Country: Great Britain
Year of production: 2001
Uses: Pre-clincal medical students; students of biochemistry and physiology
Subjects: Medical sciences
Keywords: biochemistry; cystic fibrosis

Name: Educational Broadcasting Services Trust
Address: No longer trading
Notes: Educational and training materials with an emphasis on maths, science and skills development, produced in collaboration with consortia of university and college academics and media departments under the auspices of the Educational Services Broadcasting Trust. Series include Maths for Engineers, Shotlist, and the Skillbank vocational skills training programmes. For sale on DVD or via download. Now ebst online is part of FENC. (www.fenc.org.uk). Now possibly part of Blended Learning Consortium.

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