Hormone Replacement Therapy

Synopsis
Following ovarian failure there is a 13-fold increase in plasma FSH and a 3-fold increase in luteinizing hormone together with a fall in oestrone and oestradiol to 20% of their normal follicular phase values. Oestrogen therapy will remove most of the symptoms of the climacteric but there is no doubt that unopposed oestrogens carry a risk of hyperplasia and possibly endometrial carcinoma. Hyperplasia can be prevented by giving 10 days of a progestogen with the cyclical oestrogen therapy and this should be the recommended regimen of therapy. If cystic glandular hyperplasia does occur with unopposed oestrogens it can invariably be corrected with two 21 day courses of a progestogen. Scanning electron microscopy is being used to characterise the cell surface morphology in normal hyperplastic and malignant endometrial cells.
Series
Current Research in Obstetrics & Gynaecology, Series
Language
English
Country
Great Britain
Medium
Video; Videocassette. U-matic, VHS. b&w. 30 min.
Year of production
1979
Subjects
Medical sciences
Keywords
hormone replacement therapy

Credits

Producer
J C Smith
Contributor
Geoffrey Chamberlain
Cast
John Studd 

Production Company

Name

University of London Audio-Visual Centre

Notes
Closed down.

Sponsor

Name

British Postgraduate Medical Federation

Phone
071-831 7599
Address
33 Millman Street
LONDON
WC1N 3EJ

Distributor

Name

Wellcome Film

Email
misc@wellcome.ac.uk
Web
http://wellcomelibrary.org/about-us/about-the-collections/moving-image-and-sound-collection/ External site opens in new window
Phone
020 7611 8766
Fax
020 7611 8577
Address
Moving Image & Sound Collections
Wellcome Library
183 Euston Road
London
NW1 2BE

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