Hormone Replacement Therapy
- Synopsis
- Following ovarian failure there is a 13-fold increase in plasma FSH and a 3-fold increase in luteinizing hormone together with a fall in oestrone and oestradiol to 20% of their normal follicular phase values. Oestrogen therapy will remove most of the symptoms of the climacteric but there is no doubt that unopposed oestrogens carry a risk of hyperplasia and possibly endometrial carcinoma. Hyperplasia can be prevented by giving 10 days of a progestogen with the cyclical oestrogen therapy and this should be the recommended regimen of therapy. If cystic glandular hyperplasia does occur with unopposed oestrogens it can invariably be corrected with two 21 day courses of a progestogen. Scanning electron microscopy is being used to characterise the cell surface morphology in normal hyperplastic and malignant endometrial cells.
- Series
- Current Research in Obstetrics & Gynaecology, Series
- Language
- English
- Country
- Great Britain
- Medium
- Video; Videocassette. U-matic, VHS. b&w. 30 min.
- Year of production
- 1979
- Subjects
- Medical sciences
- Keywords
- hormone replacement therapy
Credits
- Producer
- J C Smith
- Contributor
- Geoffrey Chamberlain
- Cast
John Studd
Production Company
- Name
University of London Audio-Visual Centre
- Notes
- Closed down.
Sponsor
- Name
British Postgraduate Medical Federation
- Phone
- 071-831 7599
- Address
- 33 Millman Street
LONDON
WC1N 3EJ
Distributor
- Name
Wellcome Film
- misc@wellcome.ac.uk
- Web
- http://wellcomelibrary.org/about-us/about-the-collections/moving-image-and-sound-collection/ External site opens in new window
- Phone
- 020 7611 8766
- Fax
- 020 7611 8577
- Address
- Moving Image & Sound Collections
Wellcome Library
183 Euston Road
London
NW1 2BE
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