Expert Drug Therapy Video Series

Synopsis

Each programme focuses on drug therapy for a specific disorder and uses animated sequences to demonstrate how a drug works inside the body to produce its therapeutic effects. Shows how particular drugs halt or reverse a disease process and what adverse reactions they may cause. Discusses what implications these effects have for nursing care before, during and after drug administration.
1: Illustrates how a combination of loop and thiazide-related diuretics can maximise diuresis in a patient with acute heart failure; how dubutamine stimulates beta1- and beta2-adrenegic receptors to increase cardiac output; how a phosphodiesterase inhibitor prevents the blockage of cyclic adenosine monophosphate, which reduced preload and afterload and improves cardiac output; why nitroprusside reduces afterload more dramaticlly than nitroglycerin, but poses greater risks to the patient; why an angiotensin-receptor blocker may be prescribed insead of an ACE inhibitor; how ACE inhibitors can prevent bradykinin from breaking down in the lungs, causing the characteristic ACE-inhibitor cough; why beta-adrenergic blockers may initially cause a patient’s hart failure symptoms to worsen - and how to prevent this.
2: Illustrates how the vasodilator sodium nitroprusside works quickly to lower blood pressure during a hypertensive emergency; how peripheral vascular resistance and cardiac output control blood pressure, and how different antihypertensive drugs affect those forces to reduce hypertension; how beta blockers, diuretics, angiotensin-receptor blockers, central-acting drugs, and other drugs used in long-term individualized treatment for hypertension work; how to spot adverse drug reactions and work quickly to prevent life-threatening complications; which patient-teaching measures can maximise a drug’s therapeutic effects and minimize its adverse ones; how drug therapy can be safely adapted for a patient whose hypertension is complicated by diabetes mellitus or renal insufficiency.
3: Illustrates how nitroglycerin relieves chest pain by relaxing vascular smooth muscles, which dilates coronary arteries; how thrombolytic drugs, such as alteplase, lyse and occluding thrombus, restore myocardial blood flow, and prevent necrosis of the injured myocardium; how heparin blocks the conversion of fibrinogen to fibrin and prothrombin to thrombin, thus preventing new thrombi from forming; why beta blockers are used to limit the size of an MI; how ACE inhibitors minimize left ventrical dilation by reducing afterload and blood pressure; why HMG-CoA reductase inhibitors, such as lovastatin, are used to reduce the risk of a second MI in patients with hyperlipidemia.
4: Illustrates how glucagon converts hepatic stores of glycogen into glucose; how insulin attaches to receptors on cell membranes, allowing glucose to enter cells and provide energy for metabolism; how a rapid drop in a hyperglycemic patient’s glucose level can cause cerebral edema; how sulfonylureas lower the blood glucose level by causing beta cells to produce more insulin; how gemfibrozil increases the activity of lipoprotein lipase, which helps prevent athersclerosis by removing triglycerides from chylomicrons and VLDSs in the blood; why repaglinide must be administered 15 to 30 minutes before meals.
5: Discusses which drugs control atrial fibrillation and ventricular tachycardia, and how to administer them safely and accurately; how the cardiac glycoside digoxin slows the heart rate by enhancing parasympathetic stimulation; how ibutilide slows ectopic impulse conduction in atrial fibrillation by blocking potassium movement out of myocardial cells; how heparin prevents clots from forming in the atria, and how to monitor a patient’s complete blood count for signs of heparin-induced thrombocytopenia; why the anticoagulant warfarin may be included in a patient’s continuing therapy; why a patient may be at risk of new arrhythmias or heart failure during propafenone therapy - and how to decrease the risk; why IV amiodarone must be administered using PVC tubing and a central venous catheter.
6: Discusses which drugs are used to treat an acute exacerbation of asthma and which ones are reserved for continuing therapy; how albuterol relaxes bronchial smooth muscles, causing bronchodilation and improved airflow; how the stepwise approach guides asthma treatment; how leukotriene inhbitors, such as zarfirlukast, reduce airflow inflammation by preventing cysteinyl leukotrienes from engaging with receptors; which inhalers should be used with a spacer and which ones should be inhaled directly from the mouthpiece; how ipratroprium prevents acetylcholine from stimulating cholinergic receptors on smooth-muscle cell membranes, thus reducing mucus production; how mast-cell stabilizers, such as cromolyn, prevent the release of histamine and other inflammatory substances; how to safely administer corticosteroids by inhalation, intravenously, or orally.
7: Discusses how to administer epinephrine by IV bolus, IV infusion or endotracheal intubation; why vasopressin may be used instead of epinephrine to divert blood to the coronary and cerebral blood vessels and preserve circulation to the heart and brain; how amiodarone works with defibrillation to suppress ventricular fibrillatin and prevent new arrhythmias from occurring; how to assess for adverse effects of norepinephrine therapy, such as peripheral ischemia and GI bleeding; how calcium chloride, sodium bicarbonate, and regular insulin with glucose work to help correct hyperkalemia.
8: Programme and description not available until September 2001

Language

English

Country

United States

Medium

Video; 8 videocassettes. VHS. NTSC. col. 8 x 30 min.

Year of production

1999-2001

Availability

Sale; 2001 sale: $39.95 (+p&p) each part

Uses

Practising nurses

Subjects

Medical sciences

Keywords

arrhythmias; cardiology; diabetes; drug administration; hypertension; infection control; myocardial infarction; nursing; pharmacology; respiratory diseases; vascular systems

Sections

Title

Heart failure and pulmonary edema

Synopsis

1: Illustrates how a combination of loop and thiazide-related diuretics can maximise diuresis in a patient with acute heart failure; how dubutamine stimulates beta1- and beta2-adrenegic receptors to increase cardiac output; how a phosphodiesterase inhibit

Title

Hypertension2

Synopsis

2: Illustrates how the vasodilator sodium nitroprusside works quickly to lower blood pressure during a hypertensive emergency; how peripheral vascular resistance and cardiac output control blood pressure, and how different antihypertensive drugs affect th

Title

Myocardial infarction2

Synopsis

3: Illustrates how nitroglycerin relieves chest pain by relaxing vascular smooth muscles, which dilates coronary arteries; how thrombolytic drugs, such as alteplase, lyse and occluding thrombus, restore myocardial blood flow, and prevent necrosis of the i

Title

Diabetes mellitus2

Synopsis

4: Illustrates how glucagon converts hepatic stores of glycogen into glucose; how insulin attaches to receptors on cell membranes, allowing glucose to enter cells and provide energy for metabolism; how a rapid drop in a hyperglycemic patient's glucose lev

Title

Arrythmias

Synopsis

5: Discusses which drugs control atrial fibrillation and ventricular tachycardia, and how to administer them safely and accurately; how the cardiac glycoside digoxin slows the heart rate by enhancing parasympathetic stimulation; how ibutilide slows ectopi

Title

Asthma, emphysema, and chronic bronchitis

Synopsis

6: Discusses which drugs are used to treat an acute exacerbation of asthma and which ones are reserved for continuing therapy; how albuterol relaxes bronchial smooth muscles, causing bronchodilation and improved airflow; how the stepwise approach guides a

Title

Cardiopulmonary arrest

Synopsis

7: Discusses how to administer epinephrine by IV bolus, IV infusion or endotracheal intubation; why vasopressin may be used instead of epinephrine to divert blood to the coronary and cerebral blood vessels and preserve circulation to the heart and brain;

Title

Infection

Synopsis

8: Programme and description not available until September 2001

Production Company

Name

Blanchard & Loeb Publishers

Email

service@blanchardloeb.com

Web

http://www.blanchardloeb.com External site opens in new window

Fax

+1 201 348 4505

Address

PO Box 2485
Secaucus
NJ 07096-9812
USA

Distributor

Name

Blanchard & Loeb Publishers

Web

http://www.blanchardloeb.com/ External site opens in new window

Address

Box 7975
San Francisco
CA 94120-7975