Bloodlines: A Family Legacy

Synopsis
The production of normal red blood cells is a complex process involving many genes. Mutations in the DNA can cause changed haemoglobin and potentially fatal reductions in red cell counts, as in the disease thalassaemia, or in changed regulatory mechanisms resulting in many more red cells than normal, with a consequent increase in stamina. This film shows how medical scientists identified the ‘rich blood’ mutation in the family of a Finnish Olympic skier and explores the mechanisms by which a single change in a tiny fragment of DNA can have such profound effects on blood composition and speculates that the ‘rich blood’ mutation might be used to treat thalassaemia in the future.
Series
Health and Disease, Course U205
Language
English
Country
Great Britain
Medium
Video; Videocassette. Standard formats. col. 24 min.
Year of production
1995
Availability
Sale; 2000 sale: £145.00 (+VAT +p&p)
Subjects
Medical sciences
Keywords
blood; DNA; genetics; thalassaemia

Production Company

Name

BBC Open University Productions

Distributor

Name

Open University Worldwide

Web
http://www.ouw.co.uk External site opens in new window
Phone
+44 (0) 1908 274066
Address
Walton Hall
Milton Keynes
MK7 6AA
Notes
NB. As of May 2016 Open University Worldwide are no longer distributing DVDs. They have posted this message on their website: ‘Unfortunately Open University Worldwide Limited has decided that product sales are no longer viable given the reduced funding to Higher Education institutions and diminishing demand for the products we have traditionally stocked. At present the Open University Students Association (OUSA) will continue to sell the "Good Study Guide", and we are in discussion with other possible distributors to continue to make The Open University’s products available for purchase. As soon as we have any information on other channels of distribution we will update this notice’. Some products are still available via second hand dealers on Amazon.co.uk

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