Monoclonal Antibodies

Synopsis: Describes how lymphocytes in the bloodstream of an animal will respond to the appearance of an antigen by producing antibodies to it. Explains the difference between monoclonal and polyclonal antibodies. Discusses why a method of producing antibodies in the laboratory had to be developed before a reliable supply of standard antibody could be obtained for commercial or medical use. Describes and demonstrates the technique of fusing lymphocytes with cancer cells to produce a hybrid that can survive and produce antibodes ‘in vitro’. In the laboratory lymphocytes from the spleens of immunised mice are fused with mouse myeloma cells to produce hybridomas that can be used as a source of antibody to to antigen with which the mice were immunised.
Series: Shotlist, Series
Language: English
Country: Great Britain
Medium: Video; Videocassette. Standard formats. col. 24 min.
Year of production: 1997
Availability: Sale; 1999 sale: £55.00 (+VAT +p&p) VHS, non-higher education 1999 sale: £150.00 (+VAT +p&p) higher education - master tape for re-editing and copying 2000 sale: £35.00 (+VAT inc. p&p) VHS, higher education
Notes: Reviewed by J Rossiter in ‘Journal of Biological Education’ Vol 32 No 3 (Autumn 98), p235.
Uses: 2nd-year medical students, MSc immunology and related courses, and 2nd-year BSc/HND biomedical studies.
Subjects: Biology
Keywords: antibodies; immunology; monoclonal antibodies

Name: Educational Broadcasting Services Trust
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PE32 1LS
Notes: EBST was set up in 1987, to spread specialist learning through broadcast and new media; it’s roots were in BBC and public service broadcasting. Now EBST Online is part of FENC (www.fenc.org.uk).

Name: Educational Broadcasting Services Trust
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Notes: Educational and training materials with an emphasis on maths, science and skills development, produced in collaboration with consortia of university and college academics and media departments under the auspices of the Educational Services Broadcasting Trust. Series include Maths for Engineers, Shotlist, and the Skillbank vocational skills training programmes. For sale on DVD or via download. Now ebst online is part of FENC. (www.fenc.org.uk). Now possibly part of Blended Learning Consortium.

Name: Leeds University Television
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Address: Media Services
University of Leeds
Leeds
LS2 9JT

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